nir-vana innovation network

This Israeli SME develops automatic syringes (auto-injectors), protected needles and other means for injectable drugs - both for use by patients needing to inject themselves at home, and for use of a medical staff to inject patients. Some products are owned by the company and manufactured by subcontractors, while others are under company development and owned by the partner. Most of the products are intended for sale to pharmaceutical companies that will pack and market them with their drugs to end users. One of the auto-injectors invented and developed by the company was launched in Japan in cooperation with a large U.S. pharmaceutical company. Other projects exist with pharma and syringe producers. The company develops injectable drug delivery technologies – from product concept to commercialization. It brings over 20 years of experience in developing drug delivery technologies, from product concept through regulatory approvals to commercialization. The company exhibits at conferences and events, various exhibitions abroad to introduce the new product line of safe auto-needles. Now, in the context of the safe auto-injectors and safe auto-needles developed, customers come from other US and EU pharmaceutical companies, Canada, Japan, and India. The company offers an innovative new line of customizable unique solutions: safe automatic needles (safe auto-needles) for use with any type of glass and plastic syringes, vials, or cartridges – for major pharma, generic and biosimilar companies. The offered family of injectors delivers easy injection of a wide range of medical formulations for patients with a variety of needs. The safe auto-needles are designed — and can be customized — for use with all types of syringes or primary drug containers: conventional plastic hypodermics, single- or dual-chamber prefilled syringes made of glass, plastic, or vials. A new family line includes several products: 1) for drugs coming in a prefilled glass syringe with a needle attached to the syringe, 2) for drugs in regular syringes (instead of a standard needle, a newly developed one is connected), 3) for drugs coming in vials that require pumping and 4) mixing prior to injection, 5) a protected needle for use with a regular and prefilled syringes. Additional products are in the pipeline. In order to minimize injection-related pain, a significant majority of patients prefer to control injection speed whilst also benefiting from the features of autoinjectors. The developed products offer a unique combination of features, from autoinjectors and prefilled/safety syringes: automatic needle insertion, hidden needle and passive sharps protection, reducing anxiety and perceived pain (associated with needles) combined with manual control of injection speed, reducing pain (associated with fast injections). Except for common advantages in use, each product of the family has its own special features conditioned by its specific application. As far as international requirements and standards are concerned, some products will require FDA/CE approval, etc. for the syringe/needle itself, but some will require approval together with the drug. The company is looking for: 1) customers - pharmaceutical companies, biotech/biosimilar and generic companies, manufacturing injectable generics and drugs – for a manufacturing/subcontracting agreement, 2) strategic partners – companies manufacturing disposable medical devices – injector syringes, needles, who want to add the offered products to their portfolio to sell to pharmaceutical companies producing drugs – for a licensing agreement; 3) the companies locating 1) and 2) – business companies specialized in the field - under a services agreement.