Colorectal cancer (CRC) is the second leading cause of cancer death in developed countries. Certain studies affirm that detecting precancerous polyps can reduce both colorectal cancer incidence and mortality by 30% and 50% respectively. A colonoscopy is currently considered to be the most accurate test for early detection of CRC, but it has the limitation of causing a low level of adherence in patients due to the discomfort of the test and the preparations required.
This invention provides a new screening and/or diagnostic method, both for the precancerous stage (advanced adenoma) and for CRC, based on identifying the level of certain metabolic markers present in a faeces sample collected from the patient.
Advantages & innovations
Nowadays, the main diagnosis method for CRC is colonoscopy. This method does not have a high adherence in patients and so, this new diagnostic method through biomarkers is easier to be accepted by patients as it is a non-invasive method. Thus, no break in the skin is created and there is no contact with the mucosa, or skin break, or internal body cavity beyond a natural or artificial body orifice.
Moreover, this method allows an early diagnosis of the disease in precancerous stages which is not possible at this moment.
In summary, a new method of screening, diagnosis and/or monitoring of advanced adenoma and/or colorectal cancer in patients. It will be non-invasive and able to diagnose diseases in precancerous stages.
Stage of development
Under development/lab tested
Partner sought
The Spanish (Basque) organization is offering a license agreement to experienced companies in preclinical and clinical development of medical devices and diagnostic kits interested in acquiring this technology. Moreover, this license offer seeks both options: On the one side, companies willing to commercialise, but also companies interested in enhancing the invention.
It would be preferable for the partner to be a healthcare facility so that the validation of the method can be carried out. Nevertheless, this is not compulsory.