nir-vana innovation network

The use of the most modern microdispensing technologies with the highest precision and the know-how in assay development offer enormous potential for the successful development of diagnostic and other medical technology products in a microarray format. Low volume pico- and nanolitre dispensers can be used for miniaturized assays in strip tests, microtiter plates, microelectronics, biosensors, glass-slide surfaces, cell spotting assays and lab-on-a-chip applications. A small German company is able to provide a technical solution for above-mentioned topics.
The German biotech company with its microarray division has established an advanced technology platform for microdispensing, microarrays and multiparameter analysis, offering a comprehensive range of development and production services around the microdispensing platform.
The SME is specialized in the development and production of microarrays and supports partners with an exclusive microarray printing service, from the design of the arrays to data analysis. For this all-round service the best price and performance ratio, short production times and excellent quality are provided.
There are several forms of microarrays offered by the company. The substances that can be spotted include proteins, peptides and antibodies, oligonucleotides, cells and cell lysates, carbohydrates, particles and chemical compounds as well as special molecules provided by the partner. The substrates to be spotted onto are glass and polymer slides, microtiter plates and microcavities, membranes, microfluidic chips and wafer, as well as individualized surfaces. Various surface coating technologies provide access to a wide range of applications. Depending on the partner's requirements, the array design, which concerns the number and arrangement of the spots on the substrate, is defined.
The company supports in all microarray development stages, from feasibility study, optimization, verification and validation to pilot production. Following the successful development, the company will be available with its ISO certified manufacturing capabilities as a contract manufacturing partner.
The company also offers solutions for multiparameter assay development and validation for any application in diagnostics and life sciences. The protein and antibody microarray technology has enormous potential for diagnostic applications. Miniaturized and parallelized immunoassays are ideal for generating the maximum amount of diagnostically relevant information with a small sample and reagent volumes. Customers benefit from the cost and time savings of the miniaturized assays. The use of microarrays in human and veterinary diagnostics is of interest for all applications where multiple analytes can be determined from a single sample. Typical examples for multiplex assays are allergy and food intolerance tests, the diagnosis of autoimmune, metabolic and infectious diseases as well as cancer diagnostics.
The technology platform offers excellent prospects for new ways of individualized diagnostics and personalized medicine. It is the perfect choice for the development of high-quality microarrays for diagnostics. Standard detection formats such as ELISA, lateral flow strips and microfluidics tests, as well as custom platforms can be used. In addition to the development of complete protein arrays on demand, flexible support for feasibility, design and verification as well as production and validation projects for various arrays are possible.
The company is keen to support diagnostic, biotech, food/feed labs and pharmaceutical partners through manufacturing or technical cooperation agreements. Furthermore, the SME is also open to joint research projects and any other kind of cooperation agreement suitable for both partners

Advantages & innovations

- the microarray division is equipped with a large number of different state-of-the-art microdispensing systems from different manufacturers, - both non-contact and contact spotting can be carried out, - the droplet size can be varied from 50 picoliters to the double-digit nanoliter range, for example, more than 700 spots can be placed on the bottom of one well of a 96-well microtiter plate, - the production capacity can easily be scaled up, as worktables are available in different sizes, - the focus is on the high quality of the products - for the production of the microarrays, the microdispensing system works in a climate-controlled environment with inline QC software, so that a quality control of 100 % of the produced arrays is guaranteed, - various array readers are also available for subsequent assay development, - the company can develop both colorimetric and fluorometric tests.

Stage of development

Available for demonstration

Partner sought

Diagnostic, biotech, pharma companies, food/feed safety labs, research groups are thought. The company is looking for interested partners to support them in the implementation of their ideas regarding microdispensing applications, but also in any other field that requires multiparameter assays (e.g. food safety, feed, allergies, diseases). Potential partners from Industry and research can realize their concepts with a microarray on demand from the design, pre-study, feasibility, verification and validation, until contract manufacturing (OEM). The company is looking for interested partners with need in assistance and support for the implementation of their ideas regarding microdispensing applications, but also in any other field that requires multiparameter assays (e.g. food safety, feed, allergies, diseases). Manufacturing agreement: Potential partners from Industry and research can realize their concepts with a microarray on demand from the design, pre-study, feasibility, verification and validation, until contract manufacturing (OEM). Technical cooperation agreement: The company is keen to support diagnostic, biotech, food/feed labs and pharmaceutical partners through technical cooperation agreements. The company is also open to joint research projects and any other kind of cooperation agreements suitable for both partners.