nir-vana innovation network

A long established Latvian research centre specialized in molecular biology and biomedicine has evolved into a powerful scientific centre performing basic as well as applied research in three major directions:
- molecular medicine and disease mechanisms;
- cancer research;
- structural biology, biotechnology and virusology.
The centre offers an innovative and unique personalized molecular diagnostic test for breast cancer for therapy selection and disease monitoring.
The test has been developed to deal with the problem in relation to chemotherapy that usually causes significant side effects. The mentioned set will help doctors to make appropriate treatment decisions and further monitor the progress of treatment. The set of tests consists of tumor profiling technology (somatic mutation technology) and a personalized 'liquid biopsy' test.
The Centre is looking for partners for cooperation under license agreement- both SMEs and large enterprises - working in the field of medical examination and diagnostics that perform both laboratory services and cancer examination tests

Advantages & innovations

The advantages of the proposed technology are: 1. It's non-invasive nature and the ability to provide comprehensive information on the most appropriate treatment options and response. 2. Precision diagnostics tool provides detailed tumor molecular profiling for effective and personalised treatment selection. 3. The acquired information is passed from one test to the next so that it can be used as effectively as possible. 4. Highest available accuracy. 5. Economic advantage. Innovation of the test includes: • A unique multigene panel targeting specific genes related to breast cancer. • Technology designed with unique molecular identifiers (UMIs) that provide error correction and increased accuracy during sequencing. • Test can be used both for surgery and biopsy samples. • Liquid biopsy test allows early tumor recurrence detection.

Stage of development

Prototype available for demonstration

Partner sought

The Centre is interested to find foreign experts in medical examination and diagnostic companies that perform both laboratory services and cancer examinations. Type of partner: -SMEs, large enterprises from the medical examination and diagnostic companies that perform both laboratory services and cancer examinations field. Role of partner -Under the license agreement it will provide the manual of tests to sell the product and provide services related to the use of the test.