Summary
A Ukrainian scientific institute offers probiotic, also effective as a feed additive. The basis of the preparation - two spore strains of bacteria of the genus Bacillus. The biopreparation exhibits antibacterial, antifungal, antioxidant and immunomodulatory activity, improves the digestibility of feed. The institute is interested in cooperation with enterprises that specialize in the production of microbial biopreparations. The partnership is possible on the basis of a license agreement.
Description
Over the past two decades, interest in the use of probiotics in animal husbandry has grown significantly. This is due, in particular, to the prohibition of antibiotics as growth stimulants. Probiotics are defined as "living microbiota that, when ingested in sufficient amounts, provide significant health benefits to the host". Most using probiotics are based on lactic acid bacteria, but spore-forming bacilli have several advantages over them. Bacillus sp. is attractive for use as additives to animal feed due to its higher biological activity and the ability to produce spores. They are resistant to changes in temperature and pH. They may reduce intestinal inflammation and associated disruption of gut integrity and function.
A Ukrainian R&D institute offers a biopreparation based on two bacilli strains with the following characteristics:
- Antibacterial, antifungal action is due to the synthesis of strains of antibiotic substances and bacteriolytic and yeast enzymes.
- The immunomodulatory action occurs by induction of synthesis of endogenous interferon and activation of phagocytic activity of leukocytes and macrophages.
- The antioxidant effect of the biopreparation is due to the synthesis of compounds of phenolic nature (Table.1.,2).
- The weight gain of the livestock is due to the synthesis of strains of enzymes, vitamins, amino acids, and others.
The probiotic can be used for birds, pigs, and cattle for the purpose of treating and preventing dysbiosis, intestinal and purulent infections, improving the digestibility of feed, and stimulating animal growth.
It provides:
- increase in bird survival up to 3%
- reduction or elimination of pathogenic microflora
- an increase in egg production by 3.5%.
The institute is interested in cooperation via non-exclusive license. Under the license agreement strains of bacteria, scientific and technical documentation, technology for obtaining a biopreparation will be transferred, scientific consultations will be provided.